Abstrict A device and a method for the separation of blood components in
bags, as well as an associated blood bag cup. The device comprises
a cup holder for a special double cup with two single cups and a
double chamber each, whereby in one chamber of each of the two single
cups at least one collection bag and at least one inflatable bag
is inserted and in the other chamber of each of the two single cups
at least one associated satellite bag connected via connecting hoses
to the collection bag for the separated blood plasma is inserted.
The device comprises a sensor for the detection of the separation
layer between the separated blood components in the connecting hoses
between the collection bag and the associated satellite bag. An
extremely high degree of separation with e.g. maximum plasma yield,
with purer plasma and time savings results.
Claims 1. Device for the separation of blood components in bags characterized
by the fact that the device comprises a cup holder for a special
double cup with two single cups and a double chamber for each cup,
whereby in the one chamber at least one collection bag and at least
one inflatable bag can be inserted in each of the two single cups
and in the other chamber at least one associated satellite bag for
the separated blood plasma (and if necessary for a nutrient solution
to be supplied to the collection bag) connected via connecting hoses
to the respective collection bag can be inserted into each of the
two single cups, whereby the cup holder has compressed air supplies
with check valves for the two inflatable bags and furthermore the
device comprises at least one pump for the inflating of the inflatable
bags adjacent to the collection bags and furthermore the device
comprises at least one sensor, preferably one sensor each for the
detection of the separation layer between the separated blood components
in the connecting hoses between the collection bags and the associated
satellite bags.
2. Device in accordance with claim 1 characterized by the fact
that the pump for the inflation of the inflatable bags is constructed
as a centrifugal pump, a reciprocating piston pump or a diaphragm
pump, whose speed of rotation determines the prevailing pressure
in the inflatable bags.
3. Device in accordance with claim 1 characterized by the fact
that clocked triggered magnetic clamp valves are provided, via which
the connecting hoses are guided between the collection bags and
the satellite bags so that the flow rate can be precisely controlled
4. Device in accordance with claim 1 characterized by the fact
that the inflatable bags adjacent to the collection bags can be
inflated two at least two different pressure levels p1 and p2 so
that the inflatable bags for one thing can be easily inflated to
p1 prior to centrifugation and the collection bags with this press
against the side of the cup (10) in order to prevent the formation
of folds and sedimentation clusters and for another thing the inflatable
bags can be inflated to an increased pressure p2>p1 in order
to squeeze the blood components within the collection bag from each
other via the separation layer after centrifugation and therefore
to completely separate said blood components, whereby the separated
blood components are collected in one of the satellite bags.
5. Device in accordance with claim 1 characterized by the fact
that for the two pressures p1 and p2 within the device there are
two different positions of the cup provided, which in particular
are achieved by means of a movable longitudinal slide on which the
cup holder and the cup with the bags is located.
6. Device in accordance with claim 5 characterized by the fact
that the lower pressure p1 for the "preliminary tensioning"
of the bags is assigned to an extended position of the longitudinal
slide, the cup holder and the cup and the higher pressure p2 for
the squeezing or separation of the blood components from each other
is assigned to the retracted position of the longitudinal slide,
the cup holder and the cup.
7. Device in accordance with claim 1 characterized by the fact
that the device preferably possesses a vertically extending suspension
frame for the satellite bag, whereby first hooks for the bag of
the separated blood components and second hooks for the bag containing
a nutrient solution are provided, whereby the bag for the nutrient
solution is vertically higher than the bag for the separated blood
components since the nutrient solution in particular is driven only
via gravity and is fed into the collection bag by means of one of
the clocked solenoid clamp valves.
8. Method for the separation of blood components in bags with the
device according to claim 1 characterized by the following steps:
Equipping of the double-chamber double-cup with the collection and
satellite bags, Insertion of the double-chamber double-cup into
the device for the separation of blood components in bags and inflation
of the inflatable bags to a lower pressure p1 until the collection
bags are full in their respective chambers of the double-chamber
double-cup, Removal of the double-chamber double-cup from the device
and insertion into a suitable centrifuge and centrifuging, Reinsertion
of the double-chamber double-cup into the device, Removal of the
satellite bags from the double-chamber double-cup and positioning
of the satellite bags in such a way that the connecting hoses are
guided between the collection bags and the satellite bags for the
separated blood components via at least one sensor, in particular
one sensor each, for the detection of the separation layer, Opening
of the safety shutoff valves between the collection bag and the
associated satellite bag, Inflating of the inflatable bags to an
upper pressure p2 until the separation layer in the collection
bag has migrated into the connecting hoses between the collection
bags and the satellite bags to the sensor which ends the inflation
operation of the inflatable bags, Separation of the associated satellite
bags for the separated blood components from the collection bags
and/by means of closing, in particular bonding, Optional filling
of nutrient solution into the collection bags and separation of
the associated satellite bags for the nutrient solution from the
collection bags and/by means of closing, in particular bonding,
Removal of the collection bags from the double-chamber double-cup,
as well as removal of the satellite bags from the device.
9. Method in accordance with claim 8 characterized by the fact
that the inflatable bags are only removed from the chambers of the
double-chamber double-cup in the case of a defect or for cleaning
purposes, and that they remain in the cup as a rule.
10. Method in accordance with claim 8 characterized by the fact
that the inflating of the inflatable bags takes place in particular
via at least one centrifugal pump or reciprocating piston pump or
diaphragm pump, whose speed of rotation determines the prevailing
pressure in the inflatable bag.
11. Method in accordance with claim 8 characterized by the fact
that the supplying of the nutrient solution from the satellite bag
for the nutrient solution into the collection bag takes place solely
via gravitational force.
12. Method in accordance with claim 8 characterized by the fact
that the volume flow rate of the blood components to be separated
(e.g., blood plasma) is regulated via clocked solenoid clamp valves,
in order to keep the separation layer stable.
13. Method in accordance with claim 8 characterized by the fact
that the volume flow rate of the nutrient solution is regulated
via clocked solenoid clamp valves.
14. Cup for the separation of the blood components in bags for
use in the device in accordance with claim 1 whereby the cup is
constructed as a double cup with two single cups, characterized
by the fact that each single cup of the double cup is constructed
with two chambers separate from each other, one chamber for the
collection and inflatable bags and one chamber for the satellite
bags.
15. Cup in accordance with claim 14 characterized by the fact
that the respective chambers for the satellite bags can be locked
via a chamber flap, which is linked via a hinge on the other cup
around a vertical and/or horizontal hinge axis.
16. Cup in accordance with claim 14 characterized by the fact
that between the adjacent chambers of the double-cup a hose guide
is provided, which in particular is constructed to be rotating and
which serves as a guide for the connecting hoses between the bags,
whereby as a result the connecting hoses undergo a vertical alignment.
17. Cup in accordance with claim 14 characterized by the fact
that the two cups are mirror-symmetrically adjacent to each other.
18. Cup in accordance with claim 14 characterized by the fact
that the two cups are attached to each other by a handle.
19. Cup in accordance with claim 14 characterized by the fact
that the two chambers of the two cups of the double cup for the
collection and inflatable bags are preferably indirectly or directly
adjacent to each other, and the chambers for the satellite bags
are arranged further apart from each other.
20. Cup in accordance with claim 14 characterized by the fact
that the shutoff valves for supplying compressed air to the inflatable
bags are arranged in the region of the handle preferably underneath
on the handle.
21. Cup for the separation of the blood components in bags for
use in the device in accordance with the method as per claim 8
whereby the cup is constructed as a double cup with two single cups,
characterized by the fact that each single cup of the double cup-is
constructed with two chambers separate from each other, one chamber
for the collection and inflatable bags and one chamber for the satellite
bags.
Description [0001] The invention relates to a device and a method for the separation
of blood components in bags, as well as an associated blood bag
cup, in accordance with the generic term of the independent patent
claims.
[0002] In the following only a separation of full blood in blood
plasma and erythrocytes (red blood cells) will be described, which
however, is not intended to be restrictive for the invention. Of
course the invention can also be used for an additional separation
of blood components that have already been separated, for example
to manufacture blood platelet concentrate out of pooled buffy coats.
For this reason any separation of one or more blood component(s)
of full blood or of any mixture of several blood components should
be comprised by the inventive concept.
[0003] Understood as state of the art is a conventional flexible
collection bag filled with blood/blood components and a satellite
bag for the reception of a separated blood component connected to
the flexible bag via a connecting hose and if necessary a nutrient
solution bag, whereby the bags are jointly placed in a conventional
(double)blood bag cup and centrifuged. After that the bags are taken
out of the cup and hung open individually in a squeezing device
and the blood components are separated from one another by means
of squeezing.
[0004] The disadvantage to this process is the fact that during
centrifuging the bags press hard on each other and on the side of
the cup (in particular on the bottom of the cup) and after centrifuging
is complete a relatively great force and dexterity must be applied
in removing the bags from the cup and in separating the bags from
each other, which leads to a risk of damaging the bags and hoses
and leads to relatively undesirable shaking of the collection bag
and along with it the separation layer between the separated blood
components. As a result the separated blood components partially
mix together again in the region of the separation layer and the
ratio of volumes of the separated blood components to each other
changes, that is, the degree of separation sinks undesirably. Another
disadvantage is the fact that the bags in particular in an incompletely
filled state do not fit optimally in the cup and as a result folds
and with them groups of sedimentation can form during centrifugation.
[0005] Therefore it is the object of the invention to improve a
device and a method for the separation of blood components in bags
as well as an associated blood bag cup in such a way that the degree
of separation is increased due to the fact that the blood components
separated from one another by centrifugation in the collection bag
remain separated from one another as stably as possible via the
separation layer until their complete separation from each other
by means of a squeezing device and do not mix back together again,
or only insignificantly.
[0006] The features of the independent patent claims serve the
purpose of solving the problem.
[0007] Essential in this connection for the device for the separation
of blood components in bags is the fact that the device comprises
a cup holder for a special double cup with two single cups and a
double chamber each, whereby in the one chamber of each of the two
single cups at least one collection bag and at least one inflatable
bag can be inserted and in the other chamber of each of the two
single cups at least one associated satellite bag connected via
connecting hoses to the respective collection bag for the separated
blood plasma (and if necessary for a nutrient solution to be supplied
to the collection bag) can be inserted, whereby the cup holder possesses
compressed air supplies with check valves for the two bags and furthermore
the device comprises at least one pump for the inflating of the
inflatable bags adjacent to the collection bags and furthermore
the device comprises at least one sensor, preferably one sensor
each for the detection of the separation layer between the separated
blood components in the connecting hoses between the collection
bags and the associated satellite bags.
[0008] In particular the pump for the inflation of the inflatable
bags is constructed as a centrifugal pump, but can also be a reciprocating
piston pump or a diaphragm pump or the like, whose speed of rotation
determines the prevailing pressure in the inflatable bags.
[0009] Clocked triggered magnetic clamp valves are optionally provided,
via which the connecting hoses are guided between the collection
bags and the satellite bags so that the flow rate can be precisely
controlled so that the separation layer in the collection bag remains
stable and no turbulent mixing comes into being.
[0010] Furthermore, it is optionally provided that the inflatable
bags adjacent to the collection bags can be inflated two at least
two different pressure levels p1 and p2 so that the inflatable
bags for one thing can be easily inflated to p1 prior to centrifugation
and the collection bags with this press against the side of the
cup in order to prevent the formation of folds and sedimentation
clusters and for another thing the inflatable bags can be inflated
to an increased pressure p2>p1 in order to squeeze the blood
components within the collection bag from each other via the separation
layer after centrifugation and therefore to completely separate
said blood components, whereby the separated blood components are
collected in one of the satellite bags.
[0011] In particular for the two pressures p1 and p2 within the
device there are two different positions of the cup provided, which
in particular are achieved by means of a movable longitudinal slide
on which the cup holder and the cup with the bags is located. Preferably
the lower pressure p1 for the "preliminary tensioning"
of the bags is assigned to an extended position of the longitudinal
slide, with the higher pressure p2 for the squeezing or separation
of the blood components from each other.
[0012] Furthermore the device preferably possesses a vertically
extending suspension frame for the satellite bag, whereby first
hooks for the bag of the separated blood components and second hooks
for the bag containing a nutrient solution are provided, whereby
the bag for the nutrient solution is vertically higher than the
bag for the separated blood components since the nutrient solution
in particular is driven only via gravity and is fed into the collection
bag by means of one of the clocked solenoid clamp valves.
[0013] The functions "Start", Solenoid Valve" and
"Reset" each have a control element provided
[0014] In this connection, the following steps are important for
the method of separating blood components in bags: [0015] 1. Equipping
of the double-chamber double-cup with the collection and satellite
bags, [0016] 2. Insertion of the double-chamber double-cup into
the device for the separation of blood components in bags and inflation
of the inflatable bags to a lower pressure p1 until the collection
bags are full in their respective chambers of the double-chamber
double-cup, [0017] 3. Removal of the double-chamber double-cup from
the device and insertion into a suitable centrifuge and centrifuging,
[0018] 4. Reinsertion of the double-chamber double-cup into the
device, [0019] 5. Removal of the satellite bags from the double-chamber
double-cup and positioning of the satellite bags in such a way that
the connecting hoses are guided between the collection bags and
the satellite bags for the separated blood components via at least
one sensor, in particular one sensor each, for the detection of
the separation layer, [0020] 6. Opening of the safety shutoff valves
between the collection bag and the associated satellite bag, [0021]
7. Inflating of the inflatable bags to an upper pressure p2 until
the separation layer in the collection bag has migrated into the
connecting hoses between the collection bags and the satellite bags
to the sensor which ends the inflation operation of the inflatable
bags, [0022] 8. Separation of the associated satellite bags for
the separated blood components from the collection bags and/by means
of closing, in particular bonding, [0023] 9. Optional filling of
nutrient solution into the collection bags and separation of the
associated satellite bags for the nutrient solution from the collection
bags and/by means of closing, in particular bonding, [0024] 10.
Removal of the collection bags from the double-chamber double-cup,
as well as removal of the satellite bags from the device.
[0025] The inflatable bags are only removed from the chambers of
the double-chamber double-cup in the case of a defect or for cleaning
purposes, therefore they can remain in the cup as a rule.
[0026] The inflating of the inflatable bags takes place in this
connection in particular via at least one centrifugal pump, whose
speed of rotation determines the prevailing pressure in the inflatable
bag.
[0027] The supplying of the nutrient solution from the satellite
bag for the nutrient solution into the collection bag takes place
in this connection in particular via gravitational force, but can
also take place by means of a pump in another embodiment.
[0028] The volume flow rate of the blood components to be separated
(e.g., blood plasma) is in particular regulated in this connection
via clocked solenoid clamp valves, in order to keep the separation
layer stable.
[0029] The volume flow rate of the nutrient solution is optionally
also regulated via clocked solenoid clamp valves.
[0030] However, the solenoid clamp valves can also be dropped in
another embodiment.
[0031] In this connection, it is essential for the cup for the
separation of the blood components in the bags that it is constructed
as a double-chamber double-cup with two cups, and that each cup
is constructed with two chambers separate from each other, one chamber
for the collection and inflatable bags and one chamber for the satellite
bags.
[0032] The two cups are in particular mirror-symmetrical and permanently
attached to each other by a handle.
[0033] The two chambers of the two cups of the double-cup for the
collection and inflatable bags are preferably indirectly or directly
adjacent to each other, and the chambers for the satellite bags
are arranged further apart from each other.
[0034] The respective chamber for the satellite bags is constructed
to be hinged and locking so that a chamber flap is linked via a
hinge on the other cup. In particular the hinge axis is horizontal
in the cup, but can also be vertical.
[0035] An in particular rotating constructed hose guide is arranged
between the adjacent chambers of the double-cup, which simultaneously
serves as a guide for the connecting hoses between the bags during
the centrifuging and during the squeezing (separation of the blood
components in the device), as a result of which the connecting hoses
undergo a vertical alignment.
[0036] The shutoff valves are arranged in the region of the handle
preferably underneath on the handle for supplying compressed air
to the inflatable bags.
[0037] The advantages of the afore-mentioned device and of the
method for the separation of blood components in bags, as well as
of the associated blood bag cup are an extremely high degree of
separation with e.g. maximum plasma yield, with purer plasma and
a time savings of over 50% due to the double construction of the
double-chamber double-cup.
[0038] In contrast to the squeezing devices which have been standard
up to now, which are post-connected to a conventional blood centrifugation,
here double the number, namely two blood bags, can be squeezed at
one time, which corresponds to cutting the work time in half.
[0039] Furthermore, unlike the state of the art up to now, the
blood bags do not have to be removed from the centrifuge cups and
individually suspended open into the squeezing device. The removal
of the cups which has been necessary up to now requires that one
pulls very hard because the blood bags had been compressed into
the cups very tightly and free from air. This is no longer the case
with the inventive double-flap cup, the bags remain in there. Even
by means of the most careful work it was not reliably possible to
avoid turbulence, that is, a mixing of the outer layers of the sediments.
[0040] In the inventive double-flap cup two separately connected
empty air bags are mounted underneath the handle, whose air supply
is closed by the handle upon being placed upon the slide and which
is activated by the press of a button. In the extended position
the double-cup can be supplied with a pre-selectable and set air
pressure of approximately 0.2 bar. This is applied prior to centrifugation,
in order to squeeze the inserted blood bag tightly and to prevent
a formation of folds with groups of sedimentation. The compressed
air supply on the handle has two shutoff valves, which maintain
the air pressure during removal.
[0041] After centrifugation the double-cup is lowered and inserted
with the slide onto the squeeze position, through which a force
of pressure of 0.5 bar per button press can occur. With each lowering
of the cups on the slide the shutoff valves are opened.
[0042] The satellite bags, i.e. as a rule one empty bag for the
plasma and one additional bag with up to 110 ml of nutrient solution
for the remaining packed human blood cells as well as the connecting
hoses, are placed easily into the lateral flap parts which are closed
for centrifugation and can be opened after centrifugation, in order
to ensure easy handling. The satellite bags also have a tendency
of sticking to the bottom. Thus removal from the opened cups is
much easier and effortless.
[0043] The flap parts themselves have a hinge at the bottom with
an oblong hole and two longitudinal hooks on both sides at the top,
with which they can be easily moved down for non-positive locking
and up for opening.
[0044] A wing that can be swiveled by 90.degree. is mounted above
the handle, said wing which stands for loading in the longitudinal
direction as shown in the figure and is turned by 90.degree. in
order to keep the connecting hose to the satellite bag in a vertical
position and to prevent a kinking of the hose.
[0045] The inventive device has a wire frame with suspension hooks
in which the satellite bags are hanged. The collection bag for the
plasma is placed on the lower hook while the nutrient bag for the
packed human blood cells goes on the upper hook. The supply lines
are guided over the vertically arranged sensors and further over
the pressure valves. This has the important advantage that the squeeze
flow of the plasma takes place in extensively vertical arrangement
up to the sensor, which results in a prevention of the formation
of streaks and in a far better yield of plasma.
[0046] The inventive device is a blood component separator in particular
for the automatic separation of plasma and erythrocyte concentrate
from pre-filtered banked blood in T&T blood bag systems or for
the manufacturing of blood platelet concentrates out of pooled buffy
coats.
[0047] In the use of conventional separators the centrifuged banked
blood must be removed from the centrifuge cups and attached to the
squeezing device. In the process the sediment can get fluidized
again. The inventive device on the other hand squeezes the banked
blood directly in the centrifuge cup.
[0048] Advantages: Squeezing takes place directly in the centrifuge
unit. No fluidization of the sediments caused by removal of the
bag from the centrifuge units after centrifugation. Purer plasma.
Simpler handling. Time savings: 2 units of banked blood are squeezed
simultaneously. Space savings: Compact design. Takes up little space
in comparison to conventional separators. Maximum plasma yield by
means of positioning of the sensor on the hose.
[0049] In the present invention it is a matter of giving a known
soft blood bag the tautest possible fixation, which from the beginning
prevents formation of folds, in order to prevent the development
of sediment traps in the folds. For this purpose the filled blood
bag is placed in the hinged insert cup, which is provided on the
inside with an empty air bag. The hinged auxiliary cup holds the
satellite bag and the hoses of the blood bag system and is closed
with the partition, resulting in a compact, closed cup half or insert
half, which is connected to a second half via a handle, resulting
in a double-cup blood bag unit, as has been used similarly in practice
for a long time. With the help of an air pump the two air bags are
slightly inflated, until the blood gabs no longer show any more
folds. After that the double inserts are placed into the metal cups
of the centrifuge for centrifuging.
[0050] In the centrifugation the air in the air bags is displaced
and forms an air bubble which stabilizes the connecting pieces of
the hoses and prevents buckling, which also prevents the development
of unpleasant sediment traps.
[0051] The connecting hoses can additionally be trimmed via floating
stabilization clips to the vertical position upon exiting the blood
bag, which also prevents buckling and the development of sedimentation
traps.
[0052] After successful centrifugation the double insert cups are
removed from the centrifuge, the two auxiliary cups are opened and
the satellite bags attached to the connecting hoses are taken out.
[0053] Both air bags are further inflated simultaneously via an
air pump and the protruding plasma in the blood bag is displaced
into the satellite bags, as can be precisely performed in this way
to gain pooled blood platelets.
[0054] Advantage: The centrifuged blood bag must not be carefully
or forcefully pulled out of its receptacle, as a result of which
more or less a takes place, but rather the components remain preserved
up to separation with sharp separating lines.
[0055] An unpleasant formation of folds and buckling of the connecting
pieces, in particular in the case of underfilled bags, is prevented.
[0056] In the following the invention will be described in greater
detail with the help of drawings depicting only one means of implementation.
In this connection, additional features and advantages of the invention
result from the drawings and their description.
[0057] The figures show the following:
[0058] FIG. 1: shows a perspective view of an inventive device
for the separation of blood components in bags, without showing
an associated blood bag cup;
[0059] FIG. 2: shows a perspective view of an inventive blood bag
cup in opened position;
[0060] FIG. 3: shows a perspective view of an inventive blood bag
cup in accordance with FIG. 2 in closed position;
[0061] FIG. 4: shows a perspective view of an inventive device
in accordance with FIG. 1 with representation of an associated
blood bag cup in accordance with FIGS. 2 and 3 in a first position;
[0062] FIG. 5: shows a device in accordance with FIG. 4 with representation
of an associated blood bag cup in accordance with FIGS. 2 and 3
in a second position.
[0063] In accordance with FIG. 1 the inventive device 1 for the
separation of blood components in bags consists of a case 2 and
a suspension frame 6 mounted to the case from its head for the hanging
of the nutrient solution bag on the upper hook 6a and for the hanging
of the plasma bag on the lower hook 6b, whereby the suspension frame
6 is formed in the shape of the letter "A".
[0064] The case 2 has a bulge 3 in the front region for the cup
holder 7 and consists additionally of a bottom 4 and of a top region
5 as well as consisting of sidewalls and rear walls.
[0065] In the top region 5 there are four solenoid clamp valves
21 22 present, two of them (21a, 22b) for the clamping of the connecting
hose between the collection and satellite bags and two further bags
(22a, 22b) for the clamping of the connecting hose between the collection
and nutrient solution bags. In the front of the top region 5 there
are vertical slots underneath each of the solenoid clamp valves
21 in which sensors 20 (20a, 20b) are arranged in about the middle
for the detection of the in the respective connecting hose between
the collection and satellite bags. Three actuating elements 23 are
provided between the solenoid clamp valves 21 22 in the top region
5 for "Start", "Solenoid valve on/off" and
for "Reset".
[0066] The cup holder 7 is designed for holding an inventive double
cup 10 in accordance with FIGS. 2 and 3 whereby the top, button-shaped
connections 7a, 7b are molded on for the air supply of the inflatable
bag. If the double cup 10 is placed as per FIGS. 2 and 3 on the
cup holder 7 in such a way that a single cup 10a comes to rest on
the one side and the other single cup 10b comes to rest on the other
side of the cup holder 7 then the connections 10a, 10 attach for
the air supply of the inflatable bags to check valves of the single
cups 10a, 10b, whereby these check valves are connected to the inflatable
bags (not shown here) in the outer chambers 11a, 11b (see FIGS.
2 3) of the single cups 10a, 10b.
[0067] The whole cup holder 7 is supported on a slide 8 which is
constructed in the sliding directions 9 to be moved manually or
by a motor out of/into the bulge 3 so that the positions in accordance
with FIGS. 5 and 5 result. FIG. 4 shows the slide 8 in its extended
position, which is provided for the purpose of inflating the inflatable
bags with a lower initial pressure (prior to centrifugation), in
order to squeeze the collection and the inflatable bags compact
in the chamber 11a, 11b. FIG. 5 shows the slide 8 in its retracted
position, which is provided for the purpose of inflating the inflatable
bags with a higher end pressure (after centrifugation) in order
to completely separate the centrifuged blood components from each
other by squeezing a portion out of the collection bag by means
of the inflatable bag.
[0068] FIGS. 2 and 3 show an inventive double hinged cup 10 in
opened position (FIG. 2) and in closed position (FIG. 3).
[0069] The inventive double hinged cup 10 consists of two cups
10a, 10b, which are mirror-symetrically attached to each other either
indirectly or directly, detachably or non-detachably, via a handle
18 with their chambers 11a, 11b for the collection and inflatable
bags. A chamber 12a, 12b for the satellite bags connects to the
respective chambers 11a, 11b for the removal and inflatable bags,
which each have a hinged flap part 13. This flap part 13 is swivel
connected around an axis by means of a hinge 15 with the remainder
of the chambers 12a, 12b, which in turn are connected to chambers
11a, 11b. The flap part 13 is secured during by hooks 14 which
lock into engagement in the allocated retainers 17.
[0070] All of the chambers 11 12 are constructed open at the top
and closed at the bottom, so that the respective bags can be easily
inserted.
[0071] Above the handle 18 a rotating hose guide 19 is arranged
around a normal axis, which is designed to be swiveled in a horizontal
plane. The connecting hoses (not shown) are held in an expedient
vertical position between the collection and satellite bags (not
shown) by means of hook-shaped ends of the hose guide 19 so that
an optimum, unhindered passage of liquid is made possible during
the squeezing of the blood components to be separated, but also
for the prevention of the sealing of groups of non-separated blood
components (e.g. groups of erythrocytes).
LEGEND
[0072] 1. Device for the separation of blood components in bags
[0073] 2. Case [0074] 3. Bulge [0075] 4. Bottom [0076] 5. Top region
[0077] 6. Suspension frame; 6a Hook for nutrient solution, 6b hook
for plasma [0078] 7. Cup holder; 7a, b air supply, 7c recess [0079]
8. Slide for 7 [0080] 9. Extension/retraction direction of 8 [0081]
10. Double cup; 10a first single cup; 10b second single cup [0082]
11. Chambers separated from 12 for collection bag and inflatable
bag; 11a for first single cup; 11b for second single cup [0083]
12. Hinged chambers for holding the satellite bags [0084] 13. Flap
part of 12 [0085] 14. Hook of 12 [0086] 15. Hinge between 11 and
12 [0087] 16. Axis of 15 [0088] 17. Retainers of 14 [0089] 18. Handle
[0090] 19. Hose guide [0091] 20. Sensor for separation layer, left:
20a, right: 20b [0092] 21. Solenoid clamp valve for collection bag,
left: 21a, right: 21b [0093] 22. Solenoid clamp valve for nutrient
solution bag, left: 22a, right: 22b [0094] 23. Actuating elements
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