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An absorbable surgical suture material based on monocarboxycellulose
having the general formula ##STR1## where: m is a degree of polymerization
of the initial cellulose from 250 to 3300; p is a molar fraction
of D-glucopyranose cycles in one polymer period from 0.95 to 0.05;
q is a molar fraction of cycles of d-anhydroglucuronic acid from
0.05 to 0.95; S is a molar fraction of the complex fragment of D-anhydroglucuronic
acid, metal, and ligand from 0.03 to 0.55; Me is a transition metal;
n is a valence of the transition metal; k is a coordination number
of the transition metal .gtoreq.4; Lig is polydentate ligands; Dent
is a dentation of the ligands .gtoreq.2. A method for producing
said material consists in that cellulose threads are first threaded
with nitrogen oxides, then for 0.5 to 2.0 hours treated with a 0.5-2.0-percent
solution of a salt of a transition metal with a coordination number
not less than 4 in a suitable solvent, and after this treated for
0.5 to 2.0 hours with a 1.0-2.0-percent solution of a polydentate
complexing agent in a suitable solvent.
A device for holding a surgical suture including a base, a guide
body, a cam body, a bearing member, and a spring member. The base
has a top side, a front edge, and a back edge. The guide body projects
from the top side of the base and defines a guide face having an
entrance side and an exit side. The entrance side is adjacent the
front edge and the exit side is adjacent the back edge. The cam
body is pivotally mounted to the top side and forms a toothed surface
positioned to selectively secure a surgical suture against the guide
face. The spring member is positioned between the cam body and the
bearing member, biasing the toothed surface toward the guide face.
The invention provides a surgical suture placement device that
includes a handle assembly rotatably secured to an elongated hollow
outer tube extending from the handle assembly. Also included is
a suturing assembly rotatably secured to the distal end of the elongated
hollow outer tube and a hollow flexible tube connecting the handle
assembly to the suture assembly by traversing the inside of the
elongated hollow outer tube. The device can be used for placing
a suture through the urethra and bladder neck to perform an urethrovesical
anastomosis, e.g., after removal of the prostate.
The application concerns surgical suture coated with one or more
biologically active compounds. The application discloses methods
of making coated suture, placing the coated suture in an organism,
and methods of using the coated suture in the treatment of diseases
such as cancer.
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