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The present invention relates to herbal compositions and methods
for regulating body weight, especially for promoting body weight
loss, for maintaining or controlling body weight, reducing blood
levels of circulating chemical fuels (e.g., glucose, carbohydrates,
fatty acids, and cholesterol), facilitating or promoting metabolism,
treating diabetes, treating body weight disorders, and the like.
The present invention features a novel therapy for effecting weight
loss which involves treating a subject with a sympathomimetic agent
(e.g., phentermine or a phentermine-like drug) in combination with
an anticonvulsant sulfamate derivative (e.g., topiramate) such that
the subject experiences weight loss.The combination methods of the
present invention also are effective against symptoms associated
with Syndrome X. The invention also features pharmaceutical compositions
and kits for use in the practice of these novel therapies.
The present invention provides methods for using human placental
alkaline phosphatase or an active derivative to reduce blood glucose
level in a mammal. Treatment regimens provided by the invention
maybe used to control Type 1 and Type 2 forms of diabetes in humans.
The methods and treatment regimens maybe effective to maintain the
human's blood glucose level below about 10 mM, and preferably within
the normal range of 4 mM to 7 mM. The methods and treatment regimens
may be used in combination with administration of known anti-diabetic
medicaments. Also provided by the invention is a method for inducing
weight loss or reducing an expected weight gain caused by or associated
with obesity or Type 2 diabetes. The invention further provides
a preparation for administration to a human, the preparation comprising
homogeneous purified human placental alkaline phosphatase in a physiologically
acceptable carrier.
Compositions and methods of losing weight are described that are
suitable for individuals susceptible to gastric hyperacidity or
gastroesophageal reflux. The compositions include in part a snack
food having two or more rapidly digestible carbohydrates, in which
the foodstuff or an aqueous mixture of the foodstuff and water has
a pH equal to or greater than about 6, and in which the snack is
substantially protein-free. The method of weight loss suitable for
an individual with gastric hyperacidity includes substantially limiting
the individual's caloric intake to about 1400 calories or less for
women and 1800 calories or less for men in which the caloric intake
includes one or more substantially protein-free snack foodstuffs
having two or more rapidly digestible carbohydrates, in which an
aqueous mixture of the foodstuff with water has a pH equal to or
greater than about 6 and in which the individual loses weight. |